Symptoms of Aplastic Anemia

Railroad workers, such as machinists and welders are typically exposed to asbestos, diesel exhaust and welding fumes. This exposure can lead to occupational cancers, lung issues and blood disorders.

Nick LeGrande was a talented baseball player who had dreams of pitching in a Major League game one day. These dreams began to fade after he was diagnosed anemia that was aplastic.

Signs and symptoms

The signs and symptoms will depend on how low your numbers of blood cells are. They can be severe or mild.

For example, if your platelet count is low, you might suffer from bleeding gums or nosebleeds; If it's very low, you may develop an extremely dangerous condition known as uncontrolled internal bleeding (hemorrhage). Blood tests can be used to determine the number of platelets in your blood. These include blood chemistry tests, evaluations of liver and kidney function, as well as genetic tests. In some cases doctors may request a sample from the the bone marrow (called an aspiration) or solid bone tissue (called a biopsy). These samples are checked to determine the number and type of abnormal and blood cells.

Aplastic anemia is rare. It affects both men as well as women of all ages. It might develop suddenly or be gradual and become worse with time. This condition is more prevalent in children, young adults in their 20s and 30, and seniors. People of Asian descent are more likely to experience this than people of other races.

Some things might raise the risk of developing an aplastic like exposure to toxic chemicals, certain diseases and infections or pregnancy. Autoimmune diseases could also be the cause. This is when your immune system attacks healthy cells. Infection-causing viruses could be involved, such as Epstein-Barr or hepatitis. Other causes could be related to your work environment or your lifestyle.

Diagnosis

Diesel exhaust has been a major issue for railroad workers, such as those at kansas city southern railway aml kansas city southern railway stomach cancer kansas city southern railway pulmonary fibrosis Railway, for a long time. Many of those workers have been diagnosed with occupational cancers, pulmonary conditions and blood disorders related to exposure. These harmful railroad exposures can be prevented. If you've been identified as having a blood disorder because of exposure to diesel exhaust you may be entitled compensation.

Aplastic anemia can be detected by observing severe pancytopenia as well as a marked hypocellularity of the bone marrow. Flow cytometry and studies of the chromosomal structure are typically used to confirm the diagnosis of aplastic erythemia. These tests can also identify other cytopenia-related diseases, such as hyperleukemia or myelodysplastic disorder.

Michael and Shari LeGrande watched their son Nick lose interest in baseball games and other activities. The talented athlete had become tired and lacking energy. The family's doctor noticed small red spots on his skin, which were later identified as aplastic anemia. Patients with this rare blood disease are unable to produce enough healthy blood cells, which could make them tired and more susceptible to infections and kansas city southern railway interstitial Lung disease bleeding. A bone marrow transplant is necessary to treat this rare blood disease. To find a donor, they joined the Be the Match national bone Marrow Registry.

Treatment

Every Little League pitcher dreams about throwing a perfect fastball to the Major League stadium. Nick LeGrande's hopes were shattered when he was found to be having a rare blood illness.

Treatment options for aplastic ahememia depend on your age, health and the severity and cause of the disease, as other factors. Doctors treat any underlying issues that may be responsible for the anemia that is aplastic. This might include removing an exposure to a chemical or medication, stopping the use of a particular drug or treating an infection with a virus.

Transfusions of blood can help those who suffer from aplastic ahememia increase their low red blood cell and platelet levels. Younger people with severe cases of aplasticanemia may be affected by medications such as stem cells or bone marrow transfusions. These procedures use healthy donor cells to replace damaged ones that are in the bone marrow. This allows it to produce more red blood cells. For the procedure to be successful, the cells from your donor must closely match yours. The most likely match is a close family member, however other donors may also be used.

Other options include immunosuppressants or medications that stimulate your bone marrow, which causes it to produce more blood cells. These are typically prescribed in conjunction with bone marrow transplants to improve the chances of a successful outcome. They may include cyclosporine (Gengraf, Neoral, Sandimmune) or anti-thymocyteglobulin as well as corticosteroids like prednisone (Medrol Solu-Medrol).

Prevention

Railroad workers such as machinists, Kansas City Southern Railway Interstitial Lung Disease pipefitters and electricians have long been exposed of harmful substances. When they work in confined spaces with locomotives and other railroad equipment, they can breathe diesel exhaust. If this material is deposited in their lungs, they may be affected by a range of serious illnesses, such as occupational lung diseases, cancers and blood disorders. A skilled railroad injury lawyer can examine a Kansas city Southern railway interstitial lung disease kansas city southern railway reactive airway disease kansas city southern railway copd railway cancer claim. They can also bring a lawsuit to seek compensation.